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- Alan A Sag, Richard Silbergleit, Rick E Olson, Jon Wilson, and Anant Krishnan.
- Department of Radiology, William Beaumont Hospital, Royal Oak, MI 48073, USA. alan.sag@beaumont.edu
- Spine. 2012 Oct 1;37(21):E1361-3.
Study DesignCase report.ObjectiveTo report a rare case of alkaptonuria presenting as a T1-hyperintense disc herniation.Summary Of Background DataA 46-year-old man without previous diagnosis of alkaptonuria underwent evaluation for progressive back pain revealing a T1-hyperintense disc herniation at the L3-L4 level. Discectomy recovered a blackened disc that was pathologically confirmed to be nucleus pulposus with alkaptonuric involvement. The differential diagnosis of a T1-hyperintense, T2-hypointense disc on magnetic resonance imaging is discussed, with emphasis on the pathophysiology of alkaptonuria.MethodsA single patient is reported.ResultsPathologically proven patient presentation with radiological and pathological images.ConclusionWe report a rare case of alkaptonuria presenting as a T1-hyperintense disc herniation.
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