• Palliat Support Care · Mar 2008

    Case Reports

    A case of respiratory akathisia in a cancer patient: a case report.

    • Yu Sunakawa, Makoto Wada, Tomomi Nishida, Mei Wada, Kazuhiro Araki, Hisashi Endo, Fumio Nagashima, Wataru Ichikawa, Toshimichi Miya, Hideki Onishi, Masaru Narabayashi, and Yasutsuna Sasaki.
    • Department of Clinical-Oncology, Comprehensive Cancer Center, Saitama Medical University International Medical Center, Saitama, Japan. yu_s@saitama-med.ac.jp
    • Palliat Support Care. 2008 Mar 1; 6 (1): 79-81.

    ObjectiveIt has been reported that akathisia is a neurological side effect induced by antiemetic drugs and/or antipsychotics. Akathisia can occur in any area of the body, but respiratory akathisia is an unusual type of akathisia. Cases of respiratory akathisia in cancer patients taking antiemetic drugs have not previously been reported.MethodsWe report on a case of a cancer patient taking prochlorperazine as an antiemetic drug who experienced dyspnea accompanied by severe restlessness associated with respiration. By administration of biperiden, his restlessness in respiration and dyspnea promptly disappeared.ResultsThis finding led us to conclude that this cancer patient was experiencing respiratory akathisia.Significance Of ResultsRespiratory akathisia is uncommon. It is important for cancer patients that dyspnea induced by disease progression be ruled out as a cause of the respiratory restlessness. It is necessary to consider the possibility of akathisia in patients that complain of vague anxiety, chest discomfort, or dyspnea following antipsychotic medication.

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