• Samantha E Halpern, Dimitrios Moris, Jared N Gloria, Brian I Shaw, John C Haney, Jacob A Klapper, Andrew S Barbas, and Matthew G Hartwig.
• School of Medicine, Duke University, Durham, NC.
• Ann. Surg. 2023 Feb 1; 277 (2): 350357350-357.

ObjectiveTo define textbook outcome (TO) for lung transplantation (LTx) using a contemporary cohort from a high-volume institution.Summary Background DataTO is a standardized, composite quality measure based on multiple postoperative endpoints representing the ideal "textbook" hospitalization.MethodsAdult patients who underwent LTx at our institution between 2016 and 2019 were included. TO was defined as freedom from intraoperative complication, postoperative reintervention, 30-day intensive care unit or hospital readmission, length of stay >75th percentile of LTx patients, 90 day mortality, 30-day acute rejection, grade 3 primary graft dysfunction at 48 or 72 hours, postoperative extracorporeal membrane oxygenation, tracheostomy within 7 days, inpatient dialysis, reintubation, and extubation >48 hours post-transplant. Recipient, operative, financial characteristics, and post-transplant outcomes were recorded from institutional data and compared between TO and non-TO groups.ResultsOf 401 LTx recipients, 97 (24.2%) achieved TO. The most common reason for TO failure was extubation >48 hours post-transplant (N = 119, 39.1%); the least common was mortality (N = 15, 4.9%). Patient and graft survival were improved among patients who achieved versus failed TO (patient survival: log-rank P < 0.01; graft survival: log-rank P < 0.01). Rejection-free and chronic lung allograft dysfunction-free survival were similar between TO and non-TO groups (rejection-free survival: log-rank P = 0.07; chronic lung allograft dysfunction-free survival: log-rank P = 0.3). On average, patients who achieved TO incurred approximately $638,000 less in total inpatient charges compared to those who failed TO.ConclusionsTO in LTx was associated with favorable post-transplant outcomes and significant cost-savings. TO may offer providers and patients new insight into transplant center quality of care and highlight areas for improvement.Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

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