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Revista médica de Chile · Nov 2020
Review[Anti-inflammatory therapies for SARS-COV2 infection from a hematological perspective].
- Patricio Rojas and Mauricio Sarmiento.
- Departamento de Hematología y Oncología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
- Rev Med Chil. 2020 Nov 1; 148 (11): 1640-1646.
AbstractThe pathophysiology of the inflammatory profile induced by SARS-COV2 infection has similarities with conditions of immune system activation with cytokine release such as hemophagocytic syndrome and some cases of acute graft-versus-host disease. There are encouraging results of clinical studies, performed with increasingly better methodological quality, supporting the use of targeted and specific anti-inflammatory therapy in selected groups of patients with COVID-19 with severe inflammation. In this review we describe the inflammatory pathophysiology of the disease and the recent findings about its treatment.
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