• Antimicrob. Agents Chemother. · Jan 2004

    Comparative Study

    In vitro postantibiotic effects of rifapentine, isoniazid, and moxifloxacin against Mycobacterium tuberculosis.

    • Chiu-Yeung Chan, Carrie Au-Yeang, Wing-Wai Yew, Chi-Chiu Leung, and Augustine F B Cheng.
    • Department of Microbiology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories. chiuychan@cuhk.edu.hk
    • Antimicrob. Agents Chemother. 2004 Jan 1; 48 (1): 340-3.

    AbstractPostantibiotic effects (PAEs) of rifapentine, isoniazid, and moxifloxacin against Mycobacterium tuberculosis ATCC 27294 were studied using a radiometric culture system. Rifapentine at 20 mg/liter gave the longest PAE (104 h) among the drugs used alone. The combinations of rifapentine plus isoniazid, rifapentine plus moxifloxacin, and isoniazid plus moxifloxacin gave PAEs of 136.5, 59.0, and 8.3 h, respectively.

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