• Internal medicine · Jan 2021

    Case Reports

    Renal Squamous Cell Carcinoma-related Polymyositis in a Patient with Autosomal Dominant Polycystic Kidney Disease.

    • Kanako Terakawa, Naoki Sawa, Hiroki Mizuno, Akinari Sekine, Noriko Hayami, Daisuke Ikuma, Masahiro Kawada, Rikako Hiramatsu, Keiichi Sumida, Masayuki Yamanouchi, Eiko Hasegawa, Tatsuya Suwabe, Junichi Hoshino, Keiichi Kinowaki, Kenichi Ohashi, Takeshi Fujii, and Yoshifumi Ubara.
    • Nephrology Center and Department of Rheumatology, Toranomon Hospital, Japan.
    • Intern. Med. 2021 Jan 1; 60 (8): 1237-1242.

    AbstractA 74-year-old Japanese woman diagnosed with autosomal dominant polycystic kidney disease (ADPKD) was admitted to our institute for the further examination of right-side groin pain developing in the past week. The patient was diagnosed with polymyositis (PM). Diagnostic imaging showed a mass lesion measuring 8 cm and a renal stone in the right kidney. Immediately following surgical resection of the right kidney, the patient's serum CK decreased to the normal range. A histopathological analysis showed well-differentiated squamous cell carcinoma. In conclusion, this case showed a close relationship between the occurrence of squamous cell carcinoma and the development of PM in an ADPKD patient.

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