• Antiviral research · Jun 2020

    Type 1 interferons as a potential treatment against COVID-19.

    • Erwan Sallard, François-Xavier Lescure, Yazdan Yazdanpanah, France Mentre, and Nathan Peiffer-Smadja.
    • École Normale Supérieure de Paris, 45 Rue D'Ulm, 75005, Paris, France.
    • Antiviral Res. 2020 Jun 1; 178: 104791.

    AbstractType 1 interferons have a broad antiviral activity in vitro and are currently evaluated in a clinical trial to treat MERS-CoV. In this review, we discuss preliminary data concerning the potential activity of type 1 interferons on SARS-CoV-2, and the relevance of evaluating these molecules in clinical trials for the treatment of COVID-19.Copyright © 2020 Elsevier B.V. All rights reserved.

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