• Nanomedicine · Sep 2020

    Review

    Nanomedicine as a promising approach for diagnosis, treatment and prophylaxis against COVID-19.

    • Noura H Abd Ellah, Sheryhan F Gad, Khalid Muhammad, Gaber E Batiha, and Helal F Hetta.
    • Department of Pharmaceutics, Faculty of Pharmacy, Assiut University, Assiut, 71526, Egypt.
    • Nanomedicine (Lond). 2020 Sep 1; 15 (21): 2085-2102.

    AbstractThe COVID-19 pandemic caused by the newly emerged severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) puts the world in an unprecedented crisis, leaving behind huge human losses and deep socioeconomic damages. Due to the lack of specific treatment against SARS-CoV-2, effective vaccines and antiviral agents are urgently needed to properly restrain the COVID-19 pandemic. Repositioned drugs such as remdesivir have revealed a promising clinical efficacy against COVID-19. Interestingly, nanomedicine as a promising therapeutic approach could effectively help win the battle between coronaviruses (CoVs) and host cells. This review discusses the potential therapeutic approaches, in addition to the contribution of nanomedicine against CoVs in the fields of vaccination, diagnosis and therapy.

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