• Markus Holling, Uwe Wildförster, Raphaela Verheggen, Klaus Müller, Walter Stummer, and Astrid Jeibmann.
• Department of Neurosurgery, University Hospital Münster, Münster, Germany. Electronic address: hollingm@ukmuenster.de.
• World Neurosurg. 2015 Nov 1;84(5):1493.e5-8.

BackgroundMyopericytomas are benign vascular tumors composed of perivascular myoid cells that usually arise in superficial soft tissues of the extremities.MethodsWe here report on 5 cases of myopericytoma, malignant myopericytoma, and glomangiopericytoma arising from subcutaneous, paraspinal, orbital, and sellar regions that secondarily involved the nervous system. Patients experienced orbital swelling, progressing neuropathic pain, dermatoma specific pain, and oculomotor paresis.ResultsMean age at diagnosis was 56.8 years (range, 38-74 years). After a mean follow-up of 38 months, no recurrence was detected. All tumors were unencapsulated but relatively well-circumscribed lesions, showing typical histologic and immunohistochemical features of soft-tissue myopericytoma, including one malignant case.ConclusionWe conclude that myopericytoma may affect the nervous system and for prognostic and therapeutic reasons, needs to be differentiated from other vascular tumors.Copyright © 2015 Elsevier Inc. All rights reserved.

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