• Am. J. Ophthalmol. · Nov 1981

    Relative afferent pupillary defects in optic neuritis.

    • T A Cox, H S Thompson, and J J Corbett.
    • Am. J. Ophthalmol. 1981 Nov 1; 92 (5): 685-90.

    AbstractWe measured relative afferent pupillary defects in 105 patients with various stages of optic neuritis. We detected pupillary defects in 96% of acute unilateral cases, 92% of recovered unilateral cases 91.7% of acute cases with evidence of optic neuropathy in the other eye, and 65.8% of recovered bilateral cases. With careful testing, one can find relative afferent pupillary defects in nearly all patients with unilateral optic neuritis and in most patients with bilateral disease. A patient without a pupillary defect after apparent unilateral optic neuritis frequently has evidence of disease in the other eye when visual-evoked potentials are tested.

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