• Sven Berkmann, Ingeborg Fischer, Beat Sonderegger, Stefan Fischli, and Javier Fandino.
• Department of Neurosurgery, Kantonsspital Aarau, Aarau, Switzerland. Electronic address: sven.berkmann@ksa.ch.
• World Neurosurg. 2015 Nov 1;84(5):1495.e1-4.

BackgroundSellar toxoplasmosis is associated with congenital infections or immunodeficiency. The finding of Toxoplasma bradycysts in a pituitary adenoma is very unusual.Case DescriptionAn otherwise healthy 27-year-old woman presented with secondary amenorrhea and moderately elevated prolactin levels. A macroprolactinoma was suspected on magnetic resonance imaging, and cabergoline was initiated. Although dopamine levels decreased, the tumor did not show significant shrinkage; after 2 years, transsphenoidal resection was indicated to clarify the diagnosis and to cure hyperprolactinemia. Histology showed an inactive pituitary adenoma and Toxoplasma bradycysts. Seropositivity for Toxoplasma gondii, but neither immunodeficiency nor intracerebral spread, was found. During a postoperative follow-up period of 15 months, the patient did not show any recurrence.ConclusionsSellar toxoplasmosis in conjunction with pituitary adenoma is extremely rare. Nonfunctioning lesions should be suspected in cases of sellar masses and moderate hyperprolactinemia.Copyright © 2015 Elsevier Inc. All rights reserved.

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