• Muscle & nerve · Nov 2014

    Case Reports

    Venous thromboembolism after diaphragm pacing in amyotrophic lateral sclerosis.

    • Kourosh Rezania, Ori Gottlieb, Amy Guralnick, Vivek Prachand, Bobbie J Sweitzer, Wickii Vigneswaran, Steven R White, and Raymond P Roos.
    • Department of Neurology, University of Chicago Medical Center, 5841 S. Maryland Avenue, MC 2030, Chicago, Illinois, 60637 USA.
    • Muscle Nerve. 2014 Nov 1; 50 (5): 863-5.

    IntroductionPatients with amyotrophic lateral sclerosis (ALS) are prone to venous thromboembolism (VTE) and secondary complications. Because there is an increased incidence of VTE after surgical procedures, placement of a Diaphragm Pacing System (DPS) in ALS patients as treatment for respiratory muscle weakness could potentially increase the incidence of VTE, especially in patients with limited mobility.MethodsWe implanted a DPS in 10 ALS patients who met the criteria for this procedure. They underwent a preoperative evaluation as recommended by the guidelines.ResultsWe report 2 patients with no symptoms of deep vein thrombosis (DVT) before the surgical procedure who then developed perioperative VTE.ConclusionsThese patients highlight the need to consider preoperative screening for DVT and postoperative thromboprophylaxis in high-risk ALS patients who undergo DPS placement.© 2014 Wiley Periodicals, Inc.

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