• Zhongbao Hu, Jingsheng Chen, Ping Meng, and Ming Li.
• Department of Oncology, E'zhou Central Hospital, E'zhou, Hubei Province, China.
• Medicine (Baltimore). 2021 Apr 23; 100 (16): e25478e25478.

BackgroundLong noncoding RNAs play vital roles in development and progression of lung cancers. Nuclear paraspeckle assembly transcript 1 (NEAT1) polymorphisms were reported to be closely related to lung cancer susceptibility. Recently, numerous studies have been performed to detect the association between NEAT1 polymorphisms and lung cancer susceptibility. However, their results were inconsistent and controversial. So, we carried out a meta-analysis aiming to define the association exactly.MethodsAppropriate studies were retrieved from searching Web of Science, PubMed, Scopus, and Google scholar databases, updated January 31, 2021. The pooled odds ratios with 95% confidence intervals were calculated to estimate the strength of the association between NEAT1 polymorphisms and lung cancer risk. All of the data were analyzed with Stata 16.0.ResultsThe results of this meta-analysis will be submitted to a peer-reviewed journal for publication.ConclusionThis meta-analysis will summarize the relationship between NEAT1 polymorphism and lung cancer.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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