• Curr Cardiol Rep · Jun 2020

    Comment Review

    The Role of Anticoagulation in COVID-19-Induced Hypercoagulability.

    • Juan Simon Rico-Mesa, Daniel Rosas, Ashkan Ahmadian-Tehrani, Averi White, Allen S Anderson, and Robert Chilton.
    • Department of Medicine, Division of Internal Medicine, University of Texas Health San Antonio, 7703 Floyd Curl Drive, San Antonio, TX, 78229, USA. mesajs@uthscsa.edu.
    • Curr Cardiol Rep. 2020 Jun 17; 22 (7): 53.

    Purpose Of ReviewWe aim to provide a comprehensive analysis of hypercoagulability in individuals affected by COVID-19. Our goal is to describe the hypercoagulable state related to the infection and provide guidance regarding the possible benefits of anti-coagulation with the support of evidence from current literature.Recent FindingsThe incidence of thrombotic disease in individuals affected by COVID-19 is reported as high as 31%. A significant mortality benefit has been observed with the use of therapeutic anticoagulation in high-risk individuals. Literature supports the use of scoring systems, such as the sepsis-induced coagulopathy score, to risk-stratify individuals who might benefit from anticoagulation. COVID-19-induced hypercoagulability has been demonstrated to play a significant role in overall COVID-19 outcomes. Current literature shows promising evidence with the use of therapeutic anticoagulation in high-risk individuals. Further studies are needed to better analyze the risks and benefits of anticoagulation in this specific patient population.

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