• Anil Can, Jun Xu, Victor Volovici, Ruben Dammers, Clemens M F Dirven, Calum A MacRae, and Rose Du.
• Department of Neurosurgery, Brigham and Women's Hospital, Boston, Massachusetts, USA; Harvard Medical School, Boston, Massachusetts, USA; Department of Neurosurgery, Erasmus Medical Center, Rotterdam, The Netherlands.
• World Neurosurg. 2015 Dec 1; 84 (6): 1681-5.

BackgroundAortic root dimension (ARD), an echocardiographic marker of aortopathy, has recently been associated with intracranial aneurysm eccentricity, suggesting a common underlying pathophysiology between intracranial aneurysm and aortopathy.ObjectiveTo identify specific intracranial aneurysm-related parameters that independently correlate with ARD in patients with subarachnoid hemorrhage.MethodsClinical and aneurysm-related parameters obtained from 151 patients with ruptured intracranial aneurysms, and who also underwent echocardiography with ARD measured, were examined. Univariate and multivariate analysis were performed to determine correlation of these parameters with ARD.Results151 patients who were evaluated from 2008 to 2013 were analyzed. Multivariate linear regression revealed that male gender and fusiform aneurysms were correlated with higher ARD (P < 0.01 and P = 0.041, respectively) after adjustment for other morphological and clinical variables.ConclusionsFusiform aneurysms are correlated with larger ARD than saccular aneurysms, suggesting a shared pathophysiologic mechanism with aortopathy.Copyright © 2015 Elsevier Inc. All rights reserved.

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