• H A Deutschmann, M Augustin, J Simbrunner, B Unger, H Schoellnast, G A Fritz, and G E Klein.
• Medical University of Graz, Department of Radiology, University of Hospital Graz, Auenbruggerplatz 9, A-8036 Graz, Austria. hannes.deutschmann@meduni-graz.at
• AJNR Am J Neuroradiol. 2007 Apr 1; 28 (4): 628-34.

Background And Purpose3D time-of-flight MR angiography (3D TOF MRA) may be used as noninvasive alternative to digital subtraction angiography (DSA) for the follow-up of patients with intracranial aneurysms treated with Guglielmi detachable coils (GDCs). We aimed to determine the influence of aneurysm size and location on diagnostic accuracy of 3D TOF MRA for follow-up of intracranial aneurysms treated with GDCs.Materials And MethodsTwo hundred and one 3D TOF MRAs in 127 consecutive patients with 136 aneurysms were compared with DSA as standard of reference. Sensitivity and specificity of 3D TOF MRA for detection of residual or reperfusion of the aneurysms was calculated with regard to aneurysm size and location.ResultsOverall sensitivity and specificity of MRA was 88.5% and 92.9%, respectively. Sensitivity was lower for aneurysms ConclusionThe sensitivity of 3D TOF MRA for detection of reperfusion or residual perfusion of coiled intracranial aneurysms varies considerably depending on the size of the aneurysms. No conclusions can be drawn regarding a possible influence of aneurysm location on diagnostic accuracy of 3D TOF MRA. These findings may influence the decision about whether to replace DSA by 3D TOF MRA for the follow-up of patients with intracranial aneurysms treated with GDCs.

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