• Am J Emerg Med · Oct 2021

    Case Reports

    Ventricular tachycardia converts to sinus rhythm after administration of propofol: A case report.

    • Krysta Shannon, Daniel Saltzman, Irene Li, Robert Mokszycki, and Gayle Galletta.
    • UMass Memorial Medical Center, Department of Pharmacy, 55 Lake Avenue North, Worcester, MA, United States. Electronic address: Krysta.shannon@umassmemorial.org.
    • Am J Emerg Med. 2021 Oct 1; 48: 377.e1-377.e3.

    AbstractVentricular tachycardia (VT) is a major contributor to sudden cardiac death, and pharmacologic treatment options beyond antiarrhythmics are limited. Emerging data suggest sympathetic blocking agents such as propofol are a potential management option for VT refractory to first line antiarrhythmics. Previous literature has described fixed-dose propofol boluses and continuous infusions to convert ventricular arrhythmias; however, to our knowledge, there are no reports of a weight-based dosing strategy for VT. We present the case of a patient with amiodarone-refractory VT who received a 1 mg/kg propofol bolus in preparation for cardioversion and subsequently converted to normal sinus rhythm. The patient stabilized following these interventions, transferred to a tertiary care facility, and was discharged home with an implantable cardioverter defibrillator.Copyright © 2021 Elsevier Inc. All rights reserved.

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