• J Cardiovasc Med (Hagerstown) · Dec 2016

    Case Reports

    A life-threatening presentation of eosinophilic granulomatosis with polyangiitis.

    • Enrico Ammirati, Manlio Cipriani, Francesco Musca, Edgardo Bonacina, Patrizia Pedrotti, Alberto Roghi, Arash Astaneh, Jan W Schroeder, Sandra Nonini, Claudio F Russo, Fabrizio Oliva, and Maria Frigerio.
    • aDe Gasperis CardioCenter bUnit of Allergology and Immunology, Niguarda Ca' Granda Hospital, Milan, Italy.
    • J Cardiovasc Med (Hagerstown). 2016 Dec 1; 17 Suppl 2: e109-e111.

    Abstract: Necrotizing eosinophilic myocarditis (NEM) is a life-threatening condition that needs rapid diagnosis by endomyocardial biopsy and hemodynamic support usually by mechanical circulatory systems. We present the case of a 25-year-old Caucasian man who developed a refractory cardiogenic shock due to a NEM that was supported with a peripheral veno-arterial extracorporeal membrane oxygenation associated with intravenous steroids and recovered after 2 weeks. Further instrumental investigations lead to the final diagnosis of NEM as first presentation of eosinophilic granulomatosis with polyangiitis (formerly Churg-Strauss syndrome), remarking the importance of identifying the systemic disorder that usually triggers the eosinophilic damage of the myocardium.

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