• Ulus Travma Acil Cer · May 2021

    Association of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios with in-hospital mortality in the early phase of severe trauma.

    • Dong Hun Lee, Byung Kook Lee, Sung Min Lee, Yong Soo Cho, and Seong Woo Yun.
    • Department of Emergency Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju-South Korea.
    • Ulus Travma Acil Cer. 2021 May 1; 27 (3): 290295290-295.

    BackgroundThis study aimed to examine the relationship between the immediate and early complete blood count-based scores and prognosis in trauma patients.MethodsThis retrospective observational study included adult patients admitted for severe trauma between January 2014 and December 2018. Multivariate logistic regression analysis was conducted to assess the association between the neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), and platelet-to-lymphocyte ratio (PLR), and in-hospital mortality.ResultsAmong the 288 patients included in the study, in-hospital mortality was 26.4% (n=76). Immediately after emergency department (ED) arrival, non-survivors had lower NLR (3.28 vs. 4.73) and PLR (55.73 vs. 87.21) and higher LMR (4.91 vs. 3.91) than survivors. At 6 h after ED arrival, non-survivors had lower NLR (4.98 vs. 8.37) and PLR (58.23 vs. 123.74) and higher LMR (2.88 vs. 1.69) than survivors. Results of multivariate regression analysis revealed that NLR (odds ratio [OR], 0.926; 95% confidence interval [CI], 0.881-0.973) and PLR (OR, 0.994; 95% CI, 0.990-0.998) at 6 h after ED arrival were independently associated with in-hospital mortality.ConclusionLower NLR and PLR at 6 h after ED arrival were associated with in-hospital mortality in cases of severe trauma.

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