• Eur J Anaesthesiol · Jul 1993

    Randomized Controlled Trial Comparative Study Clinical Trial

    Comparison of caudal morphine and buprenorphine for post-operative analgesia in children.

    • S Girotra, S Kumar, and K M Rajendran.
    • Department of Anaesthesiology, Maulana Azad Medical College and Associated LNJPN Hospital, New Delhi, India.
    • Eur J Anaesthesiol. 1993 Jul 1; 10 (4): 309-12.

    AbstractSixty five children aged from 1-10 years who underwent herniotomy, cystolithotomy or orchidopexy received either buprenorphine 4 micrograms kg-1 (n = 33) or morphine 50 micrograms kg-1 (n = 32) by the caudal epidural route; each thus received 0.5 ml kg-1 body weight. General anaesthesia was given for surgery. Post-operative pain and behaviour were assessed by an independent observer at 1, 4, 8, 16 and 24 h post-operatively. Caudal morphine and buprenorphine were equally effective for post-operative analgesia in children, but buprenorphine was better because of its longer duration of action and lower incidence of side effects.

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