• Harry T Mai, Daniel Croxford, Mark C Kendall, and Gildasio De Oliveira.
• Department of Anesthesiology, The Warren Alpert Medical School of Brown University, 593 Eddy Street, Providence, RI, 02903, USA. hmai1@lifespan.org.
• Can J Anaesth. 2021 Jul 1; 68 (7): 1038-1044.

PurposeClinical practice guidelines are developed to provide physicians with appraised scientific evidence and enhance their medical decision-making process. Poorly developed guidelines can have a negative impact on patient care, but the quality of clinical guidelines has not been evaluated in anesthesiology practice.MethodsWe evaluated the quality of clinical practice guidelines in anesthesiology retrieved from PubMed, Scopus, Cochrane Library, and Embase databases from August 2013 to August 2018 using a validated appraisal instrument. Exclusion criteria excluded consensus statements, editorials, non-clinical/legal-themed manuscripts, institutional protocols, research methods, and chronic pain and surgical technique guidelines.Principal FindingsA total of 96 clinical practice guidelines were included in the analysis. Seventy-one out of 96 (74%; 95% confidence interval, 65 to 83) guidelines had overall quality scores lower or equal to 5 and could not be recommended as published. Higher quality guidelines (overall score greater than 5) were published in journals with higher median [interquartile range] impact factors than lower quality guidelines (4.0 [3.5-6.5] vs 3.8 [2.3-4.7]; P = 0.02). The publication of a higher quality guideline was not associated with the year that the guideline was published or if the guideline was published by a society.ConclusionsThe overall quality of most guidelines relevant to the practice of anesthesiology were poor, and the domains applicability and rigor of development rated particularly low. Future groups developing clinical guidelines should consider using methodological support to improve the quality of guidelines relevant to the practice of anesthesiology.

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