• Michael K Obeng, Ambrosia Hernandez, Amer Dastgir, Patrick A Adegboyega, Paul Salinas, and Dennis C Gore.
• Department of Surgery, Division of Plastic and Reconstructive Surgery, The University of Texas Medical Branch, Galveston, TX 77555-0724, USA. miobeng@utmb.edu
• J Natl Med Assoc. 2004 Nov 1; 96 (11): 1507-12.

BackgroundAngiosarcoma of the scalp is a rare, aggressive, and deadly cancer that affects mainly elderly Caucasian men.ObjectivesThe insidious and masquerading presentation of angiosarcoma poses enormous diagnostic challenges for primary care providers.Patients/MethodsWe present a case of a 50-year-old black man referred for evaluation of a 3.7-cm-x-5.4-cm ulcerated, fluctuant scalp lesion that had failed to respond to different antibiotics and proper wound care.ResultsSurgical excision and subsequent histopathology revealed angiosarcoma.ConclusionsThis case report highlights the importance of high index of suspicion for early diagnosis of cancerous lesions in wounds and stresses the need to include angiosarcoma in the differential diagnosis for all face and scalp lesions, as early detection may save lives. A comprehensive literature review is also presented.

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