• Respiratory medicine · Apr 2019

    Review Comparative Study

    Acute exacerbation of interstitial lung disease after procedures.

    • William H Amundson, Emilian Racila, Tadashi Allen, H Erhan Dincer, Rade Tomic, Maneesh Bhargava, David M Perlman, and Hyun Joo Kim.
    • Department of Medicine, Division of Pulmonary, Allergy, Critical Care, and Sleep, University of Minnesota, Minneapolis, MN, United States.
    • Respir Med. 2019 Apr 1; 150: 30-37.

    AbstractInterstitial lung disease (ILD) is a category of diffuse parenchymal lung diseases characterized by inflammation and/or fibrosis. The best characterized ILD is idiopathic pulmonary fibrosis (IPF). Acute exacerbation of IPF is a dreaded occurrence with grim prognosis and suboptimal treatment options. There have been recent reports that acute exacerbation can occur in other ILDs (AE-ILD). Of note, some of these acute exacerbations follow lung procedures. This review summarizes the available information on AE-ILD and discusses the procedures reported to cause AE-ILD. We also discuss proposed mechanisms, risk factors, treatment and prognosis. This review should help to inform decision-making about risks versus benefits of procedures that are commonly recommended to diagnose ILD.Copyright © 2019 Elsevier Ltd. All rights reserved.

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