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- Bethany Hung, Zach Pennington, and Daniel M Sciubba.
- Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
- World Neurosurg. 2021 Jul 1; 151: 2-4.
AbstractNeuroblastoma is a primitive small-round-blue-cell tumor predominately found in pediatric patients. Few cases of neuroblastoma involving the adult spine have been reported. Herein we present the case of a healthy 34-year-old man treated for a large neuroblastoma involving the L3-5 vertebral bodies and prevertebral great vessels. Neoadjuvant chemotherapy led to significant cytoreduction, enabling en bloc resection of the initially unresectable tumor. Adjuvant differentiating therapy was employed, and curative radiation therapy was used to address the first instance of locoregional recurrence. The patient remains alive with stable disease more than 2 years after his initial diagnosis.Copyright © 2021 Elsevier Inc. All rights reserved.
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