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Med Monatsschr Pharm · Nov 2009
Review[Liraglutide: a human GLP-1 analogue for the treatment of diabetes mellitus type 2].
- Ellen Jahn and Tanja Sausele.
- ellen.jahn@t-online.de
- Med Monatsschr Pharm. 2009 Nov 1; 32 (11): 402-7.
AbstractThe GLP-1-receptor-agonist liraglutide (Victoza) has been approved for the treatment of diabetes mellitus type 2 in Europe. Liraglutide is the first human GLP-1 analogue which is applied once a day. Efficacy and safety of liraglutide were investigated in the broad LEAD-study-programme in comparison with placebo and other common therapeutics for the treatment of diabetes mellitus type 2. Liraglutide has been approved for the combination with metformin and/or a sulfonylurea or with metformin and a thiazolidinedione, if treatment with one or a combination of these drugs is not sufficient for an adequate blood glucose control.
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