• Tumori · Sep 2013

    Multicenter Study

    Male breast cancer: clinical features and multimodal treatment in a retrospective survey analysis at Italian centers.

    • Nicla La Verde, Elena Collovà, Sara Lonardi, Daniele Generali, Anna Moretti, Francesco Atzori, Marina Cazzaniga, Chiara Saggia, Luca Tondulli, Ilaria Marcon, Anna Lisa Gentile, Rosalba Rossello, Olga Martelli, Stefania Aglione, Gabriella Farina, Michela Cinquini, and Marina Garassino.
    • Tumori. 2013 Sep 1; 99 (5): 596-600.

    Aims And BackgroundWe report a collection of data about early breast cancer in male patients from 13 Italian institutions.Methods And Study DesignWe obtained data from patient charts and performed statistical analysis. The primary end points were overall survival and disease-free survival.ResultsA total of 205 men with invasive breast cancer was identified, with a median age of 66 years. Pathological characteristics were heterogeneous for T stage, N stage and HER2 status. Histological subtype was predominantly ductal infiltrating carcinoma. Most of them were hormone receptor positive. Mastectomy was the most common strategy. Postsurgical treatment was not standardized. Patients with large tumors were more likely to be treated with chemotherapy. Disease recurrence was associated with an ER+ and PR+ status.ConclusionsWe identified a correlation between relapse and hormone receptor expression, as is the case in female breast cancer.

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