• Ryuji Yoshioka, Kiyoshi Hasegawa, Yoshihiro Mise, Masaru Oba, Taku Aoki, Yoshihiro Sakamoto, Yasuhiko Sugawara, Eiji Sunami, Toshiaki Watanabe, and Norihiro Kokudo.
• Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
• Surgery. 2014 Mar 1; 155 (3): 478-85.

BackgroundIt remains unclear whether primary colorectal cancer and synchronous liver metastases (SLMs) should be resected simultaneously or with a staged procedure.MethodsWe reviewed the short-term outcomes of 127 patients who underwent simultaneous resection of primary colorectal cancer and SLM at our institution from January 1993 to December 2011.ResultsThe proportion of simultaneous resections was 84.7% (127 of 150 patients). There was no postoperative mortality, and the postoperative complication rate was 61.4%. Major complications occurred in 23 (18.2%) patients, and anastomotic failure occurred in 2 (1.6%). The 3-, 5-, and 10-year overall survival rates were 74%, 64%, and 52%, respectively. The median recurrence-free survival period was 7.0 months (95% confidence interval, 4.5-9.5 months) and the 5-year recurrence-free survival rate was 17%.ConclusionSimultaneous resection can be performed safely in patients with colorectal cancer and SLM.Copyright © 2014 Mosby, Inc. All rights reserved.

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