• Thorax · Oct 2015

    Observational Study

    The utility of ultrasound-guided thoracentesis and pleural biopsy in undiagnosed pleural exudates.

    • Coenraad Frederik N Koegelenberg, Elvis Malcom Irusen, Florian von Groote-Bidlingmaier, Johannes Willem Bruwer, Enas Mansour A Batubara, and Andreas Henri Diacon.
    • Division of Pulmonology, Department of Medicine, Stellenbosch University & Tygerberg Academic Hospital, Cape Town, South Africa.
    • Thorax. 2015 Oct 1; 70 (10): 995-7.

    AbstractWe assessed the utility of ultrasound to guide the selection of closed pleural biopsy technique and site and to assess the respective contributions of repeat thoracentesis and closed pleural biopsy in 100 consecutive patients with undiagnosed pleural exudates. Thoracentesis was more likely to be diagnostic in TB than malignancy (77.8% vs 31.0%, p<0.001). The addition of ultrasound-guided biopsy increased the combined yield for all diagnoses from 48.0% to 90.0% (p<0.001), for malignancy from 31.0% to 89.7% (p<0.001) and for TB from 77.8% to 88.9% (p=0.688). Our findings suggest that this minimally invasive approach has a high diagnostic yield. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

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