• Modern rheumatology · Jan 2007

    Case Reports

    Sarcoid myositis with muscle weakness as a presenting symptom.

    • Hideyasu Yamada, Wataru Ishii, Satoshi Ito, Keiichi Iwanami, Hiroshi Ogishima, Takeshi Suzuki, Mizuko Mamura, Daisuke Goto, Isao Matsumoto, Akito Tsutsumi, and Takayuki Sumida.
    • Clinical Immunology, Advanced Biomedical Applications, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan.
    • Mod Rheumatol. 2007 Jan 1; 17 (3): 243-6.

    AbstractA 54-year-old woman complaining of muscle weakness and weight loss was admitted to our hospital with suspected polymyositis. Muscle biopsy revealed Langhans-type giant cells and noncaseating granulomas. Therefore, sarcoid myositis was diagnosed. The patient was treated with prednisolone, and the symptoms improved gradually. Generally, sarcoidosis is identified clinically in patients with foggy vision or mediastinal lymphadenopathy, but muscular weakness may be an infrequently observed initial symptom. Sarcoidosis should be considered in the differential diagnosis of polymyositis.

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