• J. Thromb. Haemost. · Feb 2017

    Review Meta Analysis

    Desmopressin for treatment of platelet dysfunction and reversal of antiplatelet agents: a systematic review and meta-analysis of randomized controlled trials.

    • M J R Desborough, K A Oakland, G Landoni, M Crivellari, C Doree, L J Estcourt, and S J Stanworth.
    • NHS Blood and Transplant, John Radcliffe Hospital, Oxford, UK.
    • J. Thromb. Haemost. 2017 Feb 1; 15 (2): 263-272.

    AbstractEssentials The optimal management of patients with platelet dysfunction undergoing surgery is unclear. This meta-analysis compared perioperative administration of desmopressin to placebo. Desmopressin reduced red cell transfusions, blood loss and risk of re-operation due to bleeding. There were too few events to determine if there was a change in the risk of thrombotic events.© 2016 International Society on Thrombosis and Haemostasis.

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