• J. Am. Acad. Dermatol. · Feb 1989

    Case Reports

    Generalized melanosis in occult primary melanoma.

    • M Sexton and C R Snyder.
    • Department of Pathology, Pennsylvania State University, Milton S. Hershey Medical Center, Hershey 17033.
    • J. Am. Acad. Dermatol. 1989 Feb 1; 20 (2 Pt 1): 261-6.

    AbstractOnce encountered, generalized melanosis as a consequence of disseminated melanoma is not easily forgotten. Cases in the literature usually have resulted from primary cutaneous melanoma. A case of generalized melanosis caused by an occult primary melanoma is reported in a patient who originally complained of increased pigmentation. Findings of light microscopic studies of involved skin, pathogenesis of generalized melanosis, and possible sites of origin of the primary neoplasm are discussed.

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