• Heart and vessels · Nov 2015

    Review Case Reports

    Cardiac tamponade leading to the diagnosis of eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome): a case report and review of the literature.

    • Toshiyuki Yano, Shutaro Ishimura, Tetsuaki Furukawa, Masayuki Koyama, Marenao Tanaka, Shinya Shimoshige, Akiyoshi Hashimoto, and Tetsuji Miura.
    • Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, South-1, West-16, Chuo-ku, Sapporo, 060-8543, Japan. tyano@sapmed.ac.jp.
    • Heart Vessels. 2015 Nov 1; 30 (6): 841-4.

    AbstractEosinophilic granulomatosis with polyangiitis (EGPA), which was previously called Churg-Strauss syndrome, is a necrotizing systemic vasculitis of unknown cause accompanied by prominent eosinophilia. Cardiovascular complications, including eosinophilic myocarditis, are a major cause of mortality in this disorder. Acute pericarditis with slight pericardial effusion is a typical manifestation in EGPA, though hemodynamically significant pericardial effusion has been reported in a few cases. We report a case that initially presented with isolated cardiac tamponade, which was followed by systemic manifestations of EGPA over 3 weeks. Including the present case, previous EGPA cases with cardiac tamponade are reviewed to delineate its clinical characteristics.

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