• Rev Bras Reumatol · Sep 2014

    Case Reports

    [Acute myocardial infarction as Eosinophilic granulomatosis with polyangiitis (formerly Churg Strauss syndrome) initial presentation].

    • Wahinuddin Sulaiman, Ong Ping Seung, and Sabariah Mohd Noor.
    • Divisão de Reumatologia, Departamento de Medicina, Hospital Raja Permaisuri Bainun Ipoh, Perak, Malásia.
    • Rev Bras Reumatol. 2014 Sep 1; 54 (5): 393-6.

    AbstractEosinophilic granulomatosis with polyangiitis is a rare primary vasculitic disease characterized by hypereosinophilia, late onset asthma and extravascular eosinophil granulomas. We report a case presented initially with acute myocardial infarction which later only proceed with asthma, skin manifestations and peripheral neuropathy. Laboratory parameters showed hypereosinohpilia with negative perinuclear pattern of antineutrophil cytoplasmic autoantibodies (p-ANCA). Skin biopsy showed leucocytoclastic vasculitis with eosinophilic infiltration while coronary angiography was normal. The patient's symptoms improved with IV methylprednisolone, pulse cyclophosphamide and azathioprine. Copyright © 2014 Elsevier Editora Ltda. All rights reserved.

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