• Pediatrics · Jul 2012

    Case Reports

    Everolimus: a challenging drug in the treatment of multifocal inoperable cardiac rhabdomyoma.

    • Haci Ahmet Demir, Filiz Ekici, Arzu Yazal Erdem, Suna Emir, and Bahattin Tunç.
    • Department of Pediatric Hematology/Oncology, Ankara Children’s Hematology Oncology Education and Research Hospital, Ankara, Turkey. hdemir@hacettepe.edu.tr
    • Pediatrics. 2012 Jul 1; 130 (1): e243-7.

    AbstractPrimary cardiac tumors are rare in childhood. The most common of these are rhabdomyomas. Considering that rhabdomyomas often show spontaneous regression, close follow-up may be sufficient in hemodynamically stable cases. However, hemodynamically significant cardiac rhabdomyomas confer a risk of morbidity and mortality. Herein, we report a newborn infant with multifocal cardiac rhabdomyomas treated with everolimus. The optimal dose of the drug was 0.25 mg 2 times per day, 2 days per week. Patients with inoperable cardiac rhabdomyomas and with symptoms may be candidates for everolimus treatment.

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