• Int J Obstet Anesth · May 2021

    Review

    When does obstetric coagulopathy occur and how do I manage it?

    • R E Collis, C Kenyon, T C D Roberts, and H McNamara.
    • University Hospital of Wales, Cardiff, UK. Electronic address: Rachel.collis@wales.nhs.uk.
    • Int J Obstet Anesth. 2021 May 1; 46: 102979.

    AbstractAnticipating obstetric coagulopathy is important when obstetric anaesthetists are involved in the clinical management of women with postpartum haemorrhage. Although the incidence of coagulopathy in women with postpartum haemorrhage is low, significant hypofibrinogenaemia is associated with major haemorrhage-related morbidity and thus early identification and treatment is essential to improve outcomes. Point-of-care viscoelastic haemostatic assays, including thromboelastography and rotational thromboelastometry, provide granular information about alterations in clot formation and hypofibrinogenaemia, allow near-patient interpretation of coagulopathy, and can guide goal-directed treatment. If these assays are not available, anaesthetists should closely monitor the maternal coagulation profile with standard laboratory testing during the active phase of postpartum bleeding in order to rule coagulopathy 'in or out', decide if pro-haemostatic therapies are indicated, and assess the response to haemostatic support.Crown Copyright © 2021. Published by Elsevier Ltd. All rights reserved.

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