• Eurosurveillance · Oct 2017

    Case Reports

    Multidrug-resistant Neisseria gonorrhoeae infection with ceftriaxone resistance and intermediate resistance to azithromycin, Denmark, 2017.

    • David Terkelsen, Jacob Tolstrup, Camilla Hundahl Johnsen, Ole Lund, Larsen Helle Kiellberg HK Department of Dermatovenerology, Bispebjerg Hospital, Copenhagen, Denmark., Peder Worning, Magnus Unemo, and Henrik Westh.
    • Department of Clinical Microbiology, Hvidovre Hospital, Copenhagen, Denmark.
    • Eurosurveillance. 2017 Oct 1; 22 (42).

    AbstractWe describe a multidrug-resistant Neisseria gonorrhoeae infection with ceftriaxone resistance and azithromycin intermediate resistance in a heterosexual man in Denmark, 2017. Whole genome sequencing of the strain GK124 identified MSLT ST1903, NG-MAST ST1614 and all relevant resistance determinants including similar penA resistance mutations previously described in ceftriaxone-resistant gonococcal strains. Although treatment with ceftriaxone 0.5 g plus azithromycin 2 g was successful, increased awareness of spread of gonococcal strains threatening the recommended dual therapy is crucial.

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