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- S Demirbag, B Tander, C Atabek, I Surer, H Oztürk, and S Cetinkursun.
- Department of Pediatric Surgery, Gülhane Military Medical Academy, Ankara, Turkey. sdemirbag@gata.edu.tr
- Ann Trop Paediatr. 2005 Jun 1; 25 (2): 135-7.
Background/AimAlthough topical glyceryl trinitrate ointment (GTN) has become a popular treatment for anal fissure in adults, its use in children is still limited. We aimed to determine the effectiveness and safety of topical GTN in the long-term management of anal fissure in children, which has not yet been reported.MethodsThirty-one children with anal fissure who received topical 0.2% GTN treatment between 1997 and 1998 were evaluated in 2004.ResultsTen patients had one or more relapses after initial treatment with 0.2% GTN, all within 1 year of first onset of anal fissure. No further recurrences were diagnosed during the 4-year follow-up period.ConclusionAlthough early recurrence can occur, topical GTN ointment is effective in healing chronic anal fissures in children.
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