• Pediatric emergency care · Apr 2001

    Review Case Reports

    Bupropion overdose in an adolescent.

    • S Ayers and J D Tobias.
    • Department of Child Health, The University of Missouri, Columbia 65212, USA.
    • Pediatr Emerg Care. 2001 Apr 1; 17 (2): 104-6.

    AbstractBupropion is a relatively new monocyclic antidepressant whose mechanism of action remains unknown. In addition to its use as an antidepressant, it has also been suggested to be effective in children with attention deficit hyperactive disorder and more recently as an aid in the cessation of cigarette smoking. The latter indication has resulted in an increase in its use and therefore an increased availability in households. To date, reports of overdoses in pediatric patients are limited. We report a 14-year-old boy who ingested 1.5 to 3 g of bupropion in a suicide attempt. Previous reports of bupropion ingestions and its management are discussed.

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