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Biomedical research · Aug 2008
The effects of examination stress on salivary cortisol, immunoglobulin A, and chromogranin A in nursing students.
- Koichi Takatsuji, Yoshie Sugimoto, Shoko Ishizaki, Yasuka Ozaki, Etsuko Matsuyama, and Yukari Yamaguchi.
- Department of Health Science, School of Nursing, Osaka Prefecture University, Osaka, Japan. takatsuj@nursing.osakafu-u.ac.jp
- Biomed. Res. 2008 Aug 1; 29 (4): 221-4.
AbstractThis study aimed to assess the effects of examination stress on salivary cortisol, immunoglobulin A (IgA), and chromogranin A (CgA) in nursing students. Saliva samples were collected from 15 healthy females before and immediately after the one-hour examination, and two hours after the examination. Salivary cortisol, IgA, and CgA concentrations were determined by enzyme-linked immunosorbent assay. Both IgA and CgA concentrations statistically increased immediately after the examination (P < 0.05) and decreased two hours after the examination. No significant differences were observed between before and after the examination in the salivary cortisol concentration. These findings suggest that the acute stress due to the examination is associated with raised salivary IgA and CgA, but not cortisol.
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