• Southern medical journal · Jul 1993

    Case Reports

    Disseminated Strongyloides stercoralis infection.

    • W G Simpson, D C Gerhardstein, and J R Thompson.
    • Department of Medicine, University of Kentucky, Lexington 40536-0084.
    • South. Med. J. 1993 Jul 1; 86 (7): 821-5.

    AbstractA case of disseminated S stercoralis is an immunosuppressed patient manifested with diarrhea, a rash, and progressive respiratory insufficiency. The parasites were eradicated with thiabendazole despite continued steroid therapy, and the patient survived the hospitalization. The characteristics of S stercoralis allow it to be harbored within a host for prolonged periods of time, only to disseminate once cell-mediated immunity is suppressed. A diagnosis of strongyloidiasis should be considered in an immunocompromised patient with a petechial rash. Prompt diagnosis and initiation of thiabendazole therapy provides the greatest opportunity for patient survival. Secondary bacterial infections should be aggressively sought. Mortality from disseminated strongyloidiasis approaches 80%.

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