• Ann. Thorac. Surg. · Dec 1995

    Case Reports

    Systemic lupus erythematosus valvulitis: mitral valve replacement with a homograft.

    • S M Chauvaud, A Kalangos, A J Berrebi, A R Gaer, C Acar, and A F Carpentier.
    • Department of Cardiovascular Surgery, Hôpital Broussais, Paris, France.
    • Ann. Thorac. Surg. 1995 Dec 1; 60 (6): 1803-5.

    AbstractFor many years, valvulitis in systemic lupus erythematosus has been known to occur. Our patient was a 17-year-old girl who presented with severe mitral incompetence and renal insufficiency due to lupus valvulitis. The patient was first treated by mitral valve repair, but follow-up disclosed precocious calcification of the valve, necessitating mitral valve replacement with a cryopreserved homograft. At follow-up after 1 year, echocardiography has shown the valve to be functioning normally. A reconstructive mitral valve operation would seem to be preferable. However, a conservative operation does not alter the natural history of the disease and the progression of valve thickening and calcification.

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