• Ifrah Masood, Qi Chen, Jiayi Li, Zhihui Xu, Xiaoqian Ying, Yiming Wang, Guoqing Chen, and Limin Liao.
• Department of Urology, China Rehabilitation Research Centre, School of Rehabilitation, Capital Medical University, Beijing, China.
• Neuromodulation. 2021 Oct 1; 24 (7): 1278-1283.

ObjectivesThis retrospective study aimed to determine the effectiveness of sacral neuromodulation (SNM) on neurogenic lower urinary tract dysfunction (NLUTD) and analyze the predictive factors.Materials And MethodsFrom January 2012 to January 2020, 152 subjects with NLUTD from four medical centers in China received SNM test stimulation. Subjects were assessed via bladder diaries, postvoid residual volumes (PRVs) and neurogenic bowel dysfunction (NBD) scores before and during the testing period. Patients who showed a minimum 50% improvement in symptoms through the SNM test phase were eligible for permanent SNM implantation.ResultsThe pooled success rate for chronic urinary retention was 31.0% (40/129), which was significantly lower (p < 0.05) than the rates for frequency-urgency (64.8%, 59/91), urinary incontinence (65.2%, 30/46), and NBD score (61.7%, 82/133). The results of the risk factor analysis showed that the urinary storage symptom was a statistically significant positive predictor (p = 0.001).ConclusionsIn conclusion, SNM is an effective and reliable method for treating NLUTD, especially in patients with urinary storage symptoms. Although not all of the symptoms in every patient can be resolve, SNM still might be a superior choice together with other treatment procedures.© 2021 International Neuromodulation Society.

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