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J. Mol. Cell. Cardiol. · Nov 2008
ReviewNitric oxide signaling and the regulation of myocardial function.
- Mark T Ziolo, Mark J Kohr, and Honglan Wang.
- Department of Physiology and Cell Biology, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA. ziolo.1@osu.edu
- J. Mol. Cell. Cardiol. 2008 Nov 1; 45 (5): 625-32.
AbstractNitric oxide, which is produced endogenously within cardiac myocytes by three distinct isoforms of nitric oxide synthase, is a key regulator of myocardial function. This review will focus on the regulation of myocardial function by each nitric oxide synthase isoform during health and disease, with a specific emphasis on the proposed end-targets and signaling pathways.
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