• Terapevt Arkh · Mar 2019

    Review

    New opportunities of dual bronchodilation therapy for patients with chronic obstructive pulmonary disease.

    • S N Avdeev and N V Trushenko.
    • I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia.
    • Terapevt Arkh. 2019 Mar 30; 91 (3): 76-85.

    AbstractCurrently, combinations of long-acting beta2-agonists and long-acting anticholinergics are considered as the basic therapy for majority of patients with chronic obstructive pulmonary disease (COPD). These combinations have different pharmacological characteristics and delivery devices that provides different clinical effects and new opportunities for personalized treatment of COPD. Aclidinium/formoterol fixed combination differs from other dual bronchodilators by twice-daily dosing regimen, good safety profile and a specific delivery system. Recent information on clinical efficacy and safety of aclidinium/formoterol combination in COPD patients is given in this article.

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