• Vaccine · May 1998

    Comparative Study

    A benefit-cost analysis of two-dose measles immunization in Canada.

    • L Pelletier, P Chung, P Duclos, P Manga, and J Scott.
    • Division of Immunization, Laboratory Centre for Disease Control (LCDC), Ottawa, Canada.
    • Vaccine. 1998 May 1; 16 (9-10): 989-96.

    AbstractIn 1992, because of the limitations of the one-dose measles immunization program, the National Advisory Committee on Immunization (NACI) recommended a two-dose measles immunization program to eliminate measles. More recently, NACI recommended also a special catch-up program to prevent predicted measles outbreaks and to achieve an earlier elimination of measles. The objective of this study was to complete a benefit-cost analysis of a two-dose immunization program with and without a mass catch-up compaign compared with the current one-dose program. The resulting benefit: cost ratios vary between 2.61:1 and 4.31:1 depending on the strategy used and the age of the children targeted. Given the parameters established for this analysis, the benefits of a second-dose vaccination program against measles far outweight the costs of such a program under all scenarios.

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