• Irish medical journal · May 2012

    Case Reports

    Successful use of combined high cut-off haemodialysis and bortezomib for acute kidney injury associated with myeloma cast nephropathy.

    • F Ward, O Dunne, T B Crotty, D Fennelly, A Watson, and J Holian.
    • Department of Nephrology, St Vincent's University Hospital, Dublin 4. fward79@hotmail.com
    • Ir Med J. 2012 May 1; 105 (5): 148-9.

    AbstractWe present the case of a 58-year old female with de novo dialysis-dependent acute kidney injury (AKI) secondary to myeloma cast nephropathy. The patient underwent extended high cut-off haemodialysis (HCO-HD), in conjunction with bortezomib-based chemotherapy, and soon became dialysis independent with normal renal function. To our knowledge, this is the first time this treatment strategy has been employed successfully in an Irish centre.

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