• Acta Otorhinolaryngol Ital · Jun 2005

    Case Reports

    Maxillo-ethmoidal chloroma in acute myeloid leukaemia: case report.

    • E Ferri, C Minotto, F Ianniello, S Cavaleri, E Armato, and P Capuzzo.
    • Otorhinolaryngology Unit, Surgical Department, Hospital of Dolo, Venice, Italy. emaferri@libero.it
    • Acta Otorhinolaryngol Ital. 2005 Jun 1; 25 (3): 195-9.

    AbstractChloroma, also called Granulocytic Sarcoma or Myeloid Sarcoma, is a rare malignant extra-medullary neoplasm of myeloid precursor cells. It is usually associated with myelo-proliferative disorders but its appearance may precede the onset of leukaemia. Chloroma may be found in several extracranial sites. Involvement of the head and neck region is uncommon. Differential diagnosis is often difficult and includes acute lymphoblastic leukaemia, large cell NHL, lymphoblastic lymphoma and Ewing's sarcoma. The case is presented of a maxillo-ethmoidal chloroma occurring in a case of poor prognosis acute myeloid leukaemia, emphasizing the clinical and cyto-histological features and problems concerning differential diagnosis.

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