• Preethi Ramchand, Dylan P Thibault, James A Crispo, Joshua Levine, Robert Hurst, Michael T Mullen, Scott Kasner, and Allison W Willis.
• Department of Neurocritical Care, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania; Department of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania. Electronic address: Preethi.Ramchand@uphs.upenn.edu.
• J Stroke Cerebrovasc Dis. 2018 Oct 1; 27 (10): 2632-2640.

ObjectiveMechanical thrombectomy after acute ischemic stroke has been shown to improve clinical outcomes. Data on short-term hospitalization outcomes after thrombectomy are needed. Our objective was to quantify 30- and 90-day readmissions after thrombectomy and identify factors associated with readmissions.MethodsRetrospective observational analysis of adult patients hospitalized between January and November 2014, using data from the 2014 Nationwide Readmissions Database. Readmission rates were calculated and examined according to patient, clinical, and hospital characteristics using descriptive statistics. Weighted unconditional logistic regression models estimated the odds of readmission and examine the associations between select characteristics and readmission.Results4850 individuals who underwent mechanical thrombectomy for acute ischemic stroke in 2014 were eligible for 30-day readmissions analyses. The nonelective readmission rate was 12.5% at 30 days, 20.7% at 90 days. Sepsis and stroke were the most common reasons for readmission. Female sex (adjusted odds ratio [AOR] 1.34, 1.02-1.77 at 30 days), discharge to inpatient postacute care facility (AOR 1.61, 1.07-2.41 at 30 days, AOR 1.99, 1.47-2.69 at 90 days), and longer initial length of stay (AOR 1.52, 1.04-2.23 at 30 days, AOR 1.67, 1.14-2.43 at 90 days) were associated with a higher likelihood of readmission. Thrombectomy complications were rare and not associated with readmission.Conclusions1 in 8 thrombectomy patients had a short-term readmission in 2014. Characteristics suggestive of a complicated hospital course or greater physical disability were the primary predictors of readmission. This study provides preliminary data for evaluations of the public health impact of mechanical thrombectomy in real world settings.Copyright © 2018. Published by Elsevier Inc.

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