• Cardiol J · Jan 2016

    Paravalvular leak after transcatheter aortic valve implantation (TAVI): Short-term results. Data from Polish national POL-TAVI registry.

    • Paweł Kleczyński, Wojciech Zasada, Maciej Bagieński, Łukasz Rzeszutko, Danuta Sorysz, Robert Sobczyński, Jarosław Trębacz, Bogdan Kapelak, Marian Zembala, and Dariusz Dudek.
    • Institute of Cardiology, Jagiellonian University, Krakow, Poland. kleczu@interia.pl.
    • Cardiol J. 2016 Jan 1; 23 (2): 163-8.

    BackgroundThe authors analyzed data from Polish national POL-TAVI registry in terms of paravalvular leak (PVL) occurrence after transcatheter aortic valve implantation (TAVI) and its impact on clinical outcomes.MethodsA total of 331 patients with severe aortic stenosis underwent TAVI (Edwards Sapien, n = 141; CoreValve, n = 190). The grade of PVL and survival rate were assessed at6-month follow-up.ResultsOne hundred and eighty-one (54.7%) patients developed mild PVL, and 22 (6.6%) - moderate PVL after TAVI. No severe PVLs were observed. Occurrence of moderate PVL was device dependent and more frequent in the CoreValve group (p = 0.02). Larger CoreValve device used correlated with the grade of PVL (Spearman: r = 0.19; p = 0.01), but for Edwards Sapien devices this correlation was inverted (Spearman: r = -0.62; p = 0.01). Six-month mortality rate was not significant between patients with no or mild PVL compared to those with moderate PVL (p = 0.12).ConclusionsThe PVL occurrence remains a frequent problem after TAVI and is device de-pendent, more common with Edwards 23 mm valve and 31 mm CoreValve prosthesis.

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