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Randomized Controlled Trial Comparative Study Clinical Trial
A comparison of narrow band phototherapy (TL-01) and photochemotherapy (PUVA) in the management of polymorphic light eruption.
- D Bilsland, S A George, N K Gibbs, T Aitchison, B E Johnson, and J Ferguson.
- Department of Photobiology, Ninewells Hospital and Medical School, Dundee, U.K.
- Br. J. Dermatol. 1993 Dec 1; 129 (6): 708-12.
AbstractTwenty-five patients suffering from severe polymorphic light eruption (PLE) were randomized to either photochemotherapy (PUVA) or narrow-band phototherapy (TL-01 UVB) treatment in early spring; patients receiving UVB were given placebo tablets to achieve a matching therapy procedure. During the 4 months following treatment, patient exposure to solar UVB was monitored with polysulphone badges. PLE occurrence, severity, and restriction of outdoor activity were recorded, using weekly diary-sheets. Analysis of covariance on this data, using the logarithm of UVB exposure as the explanatory variable, showed no significant differences between the treatments. TL-01 UVB is an effective alternative to PUVA in the management of PLE.
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